Is Prostate Cancer Inherited Genetically?

Thursday, April 18, 2019
Illustration of prostate cancer and genetic, credit to Invitae
There are many factors that believed to increase the risk to get prostate cancer; some of them are genetics, diet, age, race, lifestyle, obesity and Sexually transmitted diseases (STDs). 
From genetic view point, prostate cancer is highly heritable; the inherited risk of prostate cancer has been estimated to be as high as 60%. 
Men diagnosed with prostate cancer are highly probably coming from close relative (a father or a brother) with prostate cancers. 
Memorial Sloan Kettering Cancer Center (2016) suggested that a man with one close relative with prostate cancer is twice as likely to develop cancer.
Then, If two close male relatives are affected, the risk of developing prostate cancer is increased five-fold compared to man with no family members diagnosed.
There are several hundred genes implicate to different stages of Prostate Cancer. 
Maqungo et al, (2011) informed that South African National Bioinformatics Institute, University of the Western Cape has developed database called as Dragon Database of Genes associated with Prostate Cancer (DDPC). 
Data were collected from sources of around the world. Some of genes connected to prostate cancers are BRCA1, BRCA2, and HOXB13. 
If these genes have mutated due to un-known reasons, men will have a higher risk of developing prostate cancer and, in some cases, other cancers during their lifetimes.

References
Maqungo, M., Kaur, M., Kwofie, SK., Radovanovic, A., Schaefer, U., Schmeier, S., Oppon, E., Christoffels, A., and Bajic, VB. 2011. DDPC: Dragon Database of Genes associated with Prostate Cancer. Nucleic Acids Res. 2011 Jan; 39(Database issue): D980–D985. Retrieved from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013759/
Memorial Sloan Kettering Cancer Center. 2016. Inherited Risk for Prostate Cancer. Retrieved from https://www.mskcc.org/cancer-care/risk-assessment-screening/hereditary-genetics/genetic-counseling/inherited-risk-prostate




16 comments:

  1. My grandfather didn't have it.
    My father didn't have it.
    I get an annual prostate check.
    Crossing my fingers.
    Speaking of fingers...

    ReplyDelete
    Replies
    1. It is just "highly possibility" the chance to have cancer... there are many factors other than genetic, include environments....

      Hope, everything goes well with you....

      Happy Easter

      Delete
    2. Thank you to visit my article:
      Is Prostate Cancer Inherited Genetically?
      @
      Illustration of prostate cancer and genetic, credit to Invitae

      Delete
    3. Is, Prostate Cancer Inherited Genetically?
      @
      There are several hundred genes implicate to different stages of Prostate Cancer.

      Delete
  2. wow I didn't realize it was 1 in 7.

    ReplyDelete
    Replies
    1. Thank you to visit my article:
      Is, Prostate Cancer Inherited Genetically?
      @
      There are many factors that believed to increase the risk to get prostate cancer; some of them are genetics, diet, age, race, lifestyle, obesity and Sexually transmitted diseases (STDs).

      Delete
    2. Is, Prostate, Cancer Inherited Genetically?
      @
      Maqungo et al, (2011) informed that South African National Bioinformatics Institute, University of the Western Cape has developed database called as Dragon Database of Genes associated with Prostate Cancer (DDPC).

      Delete
  3. Replies
    1. Thank you to visit my article:
      Is, Prostate, Cancer Inherited Genetically?
      @
      From genetic view point, prostate cancer is highly heritable; the inherited risk of prostate cancer has been estimated to be as high as 60%

      Delete
    2. Is, Prostate, Cancer, Inherited Genetically?
      @
      Data were collected from sources of around the world. Some of genes connected to prostate cancers are BRCA1, BRCA2, and HOXB13.

      Delete
  4. That cancer never affected any man of my family, thanks god.
    Xoxo

    marisasclosetblog.com

    ReplyDelete
    Replies
    1. You are so lucky....

      Thank you to visit my article:
      Is, Prostate, Cancer, Inherited Genetically?
      @
      Men diagnosed with prostate cancer are highly probably coming from close relative (a father or a brother) with prostate cancers.

      Delete
  5. never thought of whether it was genetic.

    ReplyDelete
    Replies
    1. Thank you to visit my article:
      Is, Prostate, Cancer, Inherited, Genetically?
      @
      Memorial Sloan Kettering Cancer Center (2016) suggested that a man with one close relative with prostate cancer is twice as likely to develop cancer.

      Delete
  6. We know a few people who have this disease and all have had some family members suffer from it. So sad!

    ReplyDelete
    Replies
    1. Thank you to visit my article:
      Is Prostate Cancer Inherited Genetically?
      @
      Then, If two close male relatives are affected, the risk of developing prostate cancer is increased five-fold compared to man with no family members diagnosed.

      Delete